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Every 2.8 seconds a person dies of sepsis.

Protect yourself and your loved ones: Learn more about the risks, causes, symptoms and how to prevent sepsis.

What is Sepsis?

Sepsis occurs when the body’s response to an infection attacks its own tissues and organs. If not detected early and treated quickly, it can lead to shock, multi-organ failure and death.
0 %

of all deaths worldwide are associated with sepsis


cases per year

0 %

of sepsis cases occur outside of a hospital

Tess´s Sepsis Story:
How I Survived Sepsis 

My name is Tess Willemse, I’m from the Netherlands, and I’m 18 years old. This is my story about how I almost lost my life to a ‘lung infection.’


Common sources of sepsis

Sepsis is always caused by an infection. It can arise when bacteria, viruses or fungi enters the bloodstream through a wound, as well as through infections such as pneumonia, meningitis,urinary tract infections, seasonal flu or COVID-19.

From a Local Infection to a Body-Wide Injury

A local infection, such as pneumonia, can overcome the body‘s local defense mechanisms. Invading microorganisms and the toxins they produce induce a powerful immune response involving the whole body which can be so intense that the body loses control. The “dysregulated” response can result in injury to tissues and organs, and is known as sepsis.

Cardio-circulatory failure can develop, leading to a sudden drop in blood pressure. This is called septic shock. Several organs then stop functioning sequentially or simultaneously. This multi-organ failure often leads to death.

The Heartbreaking Story of Maddy Jones:
Born 1998, Taken by Sepsis in 2017

Maddy – a passionate and determined young woman with a promising future, whose life ended far too soon. Her parents are left wondering: ‘What if we had known about Sepsis?’ – Would she still be here?

Slurred speech or confusion

Extreme shivering or muscle pain/fever

Passing no urine all day

Severe breathlessness

It feels like you are going to die

Skin mottled or discolored


Symptoms of Sepsis

The symptoms of sepsis are varied and not easy to identify. Fever, rapid pulse, changes in consciousness and shortness of breath may be signs of sepsis.

Risk Groups

Everyone can get sepsis. People with a weak immune system are at higher risk.

People with chronic disease of the lung, liver or heart


People with diabetes or HIV / AIDS


People without a spleen


Adults over 60


Infants under 1

Michael’s Sepsis Story: The Rusty Nail That Almost Killed Me

After Micheal Porter scraped his hand against a nail while he was repairing his garden gate at his home in 2015, he didn’t think much of it. 72 hours later, he was in a coma.

You Can Prevent

Unforeseen infections can happen anywhere, but there is a lot you can do to prevent sepsis.




Clean Water


Hand Hygiene


Safe Childbirth



→ Sadness

→ Difficulty Swallowing

→ Muscle Weakness

→ Clouded Thinking

→ Difficulty Sleeping

→ Poor Memory

→ Difficulty Concentrating

→ Fatigue

→ Anxiety


Post Sepsis Symptoms

Knowing about Post Sepsis Symptoms can provide you or your loved ones with opportunities to be proactive during recovery.

You can help #StopSepsis and #SaveLives Get involved at

The lack of knowledge makes sepsis the number one preventable cause of death worldwide. World Sepsis Day (WSD) was established in 2012 with the aim of raising public awareness, but also to show support and solidarity with people who lost their loved ones, or as sepsis survivors, suffer from long-term consequences of sepsis.

Raise awareness and share this page:

Get More Information about Sepsis

Knowledge can save lives! Increase awareness of sepsis and World Sepsis Day in your network by sharing information. All materials are free for non-commercial use.
Sepsis Fact Sheet
Fact sheet on sepsis, summarizing the most crucial facts on sepsis in one page (PDF)
Sepsis Broschure

Brochure for sepsis survivors, their families, and loved ones, discussing life after sepsis, post-sepsis symptoms, consequences of sepsis, and much more.

Pocket Cards

Pocket cards for laypeople to recognize sepsis in adults, pregnant women, newborns, and children.

21 infographics highlighting different aspects of sepsis, incl. World Health Days.

The role of CytoSorb® therapy in the management of sepsis

Cytokines play a crucial role in the evolution of sepsis. The CytoSorb® adsorber is indicated, among other things, for use in conditions where elevated levels of cytokine exist. By removing elevated levels of inflammatory mediators like cytokines the CytoSorb® adsorber is intended to attenuate the dysregulated immune response, a fundamental problem in sepsis, which is not directly addressed by standard therapy. A more balanced immune response shall be achieved and so recovery of the patient supported.

CytoSorb®️ is approved in the European Union with distribution in over 75 countries around the world and to date, more than 200,000 individual applications have been performed in more than 800 clinical settings worldwide, with the treatment being well tolerated and safe.