Monocenter studies

Numerous well-known German and international hospitals are currently performing monocentric scientific studies on the efficacy and clinical effects of the use of CytoSorb in a variety of hyper-inflammatory conditions (e.g. sepsis, septic shock, acute pancreatitis, trauma, and consequences of cardiopulmonary bypass in cardiac surgery). Several studies in other fields of application such as burn injury or liver failure are in preparation.

In addition to company-sponsored studies, we are pleased to have more than 50 investigator-initiated studies in progress with approximately 20 trials actively recruiting, seven having been completed, and the rest in various stages of planning or execution.

Because of the number of projects that are currently close to completion of the clinical phase, or already completed, we expect an increase in published evidence on the effectiveness and clinical outcomes of CytoSorb therapy in these applications in the coming months.
As more studies begin enrolling, they will be detailed here.

Overview of currently ongoing monocentric studies:

CytoSorbents study ID

Category

Country 

Site

Patient No.

Status

Registration

S08

Septic shock

Germany

Greifswald University

20

Published

Link

S07

Septic shock

Hungary

Szeged University

20

Published

Link

CSI04

Cardiopulmonary bypass intraoperative

Germany

Hamburg University

40

Published

Link

S10.111-3

Cardiopulmonary bypass intraoperative

Austria

Vienna University

40

Published

Link

CSI03

Cardiopulmonary bypass intraoperative

Germany

Cologne University

300

Data analysis

Link

CSI02

Cardiopulmonary bypass intraoperative

Germany

Bochum University

40

Data Analysis

Link

CSP01

Cardiopulmonary bypass postoperative

Germany

Rostock University

10

Recruiting

Link

CSI06

Cardiopulmonary bypass intraoperative

Germany

Nuremberg hospital

40

Recruiting

Link

PCIV03

Influence on antibiotic/immunosuppressive therapy

Germany

Rostock University, Fraunhofer institute

lab test

Publication phase

S15

Septic shock/influence on antibiotic therapy

Germany

Munich University

20

Recruiting

S12

Septic shock

Germany

Munich Technical University

128

Recruiting

Link

S07

Septic shock / influence on antibiotic therapy

Germany

Duesseldorf University

30

Recruiting

Link

S10.111-11

Cardiopulmonary bypass intraoperative

Slovenia

Ljubljana University

60

Data Analysis

Link

CSI07

Cytokine clearance during cardiopulmonary bypass

Switzerland

Lausanne

15/15

published

Link

CSI11

Cardiopulmonary bypass

Russia

Research Institute for Complex Problems of Cardiovascular diseases, Kemerovo.

100

Data Analysis

Link

Tx04

Orthotopic Heart Transplantation

Hungary

Semmelweis University, Budapest

60

Recruiting

Link

CGS01

Post arrest

Switzerland

Centre Hospitaliser Universitaire, Vaudois, Lausanne

40

In preparation

Link

CGS02

Post arrest requiring eCPR

Germany

Freiburg University Hospital, Freiburg

20

In preparation

Link

EC03

Reanimation and ECMO

Germany

Hamburg University Hospital Hamburg – Eppendorf, Hamburg

40

Recruiting

Link